Abstract Background Comfort is a primary patient objective and central to patient experience, and thus, maximising comfort is a universal goal for healthcare.However, comfort is a complex concept that is difficult to operationalise and evaluate, resulting in a lack of scientific and standardised comfort care practices.The Comfort Theory developed b
Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model.
Prostate cancer patients with high WNT5A expression in their tumors have been shown to have more favorable prognosis than those with low WNT5A expression.This suggests that reconstitution of Wnt5a in low WNT5A-expressing tumors might be an attractive therapeutic approach.To explore this idea, we have in the present study used Foxy-5, a WNT5A mimick
Impact of COVID-19 on hospital admission of acute stroke patients in Bangladesh.
BackgroundWith the proposed pathophysiologic mechanism of neurologic injury by SARS CoV-2, the frequency of stroke and henceforth the related hospital admissions were expected to rise.This paper investigated this presumption by comparing the frequency of admissions of stroke cases in Bangladesh before and during the pandemic.MethodsThis is a retros
The record precipitation and flood event in Iberia in December 1876: description and synoptic analysis
The first week of December 1876 was marked by extreme weather conditions that affected the south-western sector of the Iberian Peninsula, leading to an all-time record flow in two large international rivers.As a direct consequence, several Portuguese and Spanish towns and villages located in the banks of both rivers suffered serious flood damage on
Assessing Electroencephalography as a Stress Indicator: A VR High-Altitude Scenario Monitored through EEG and ECG
Over the last decade, virtual reality (VR) has become an increasingly accessible commodity.Head-mounted display (HMD) immersive technologies allow researchers to simulate experimental scenarios that would be unfeasible or risky in real life.An example is extreme heights exposure simulations, which can be utilized in research on stress system mobili